Fluorescence lifetime imaging for disease detection and surgical guidance - Fluorescence lifetime imaging (FLIm) is an optical imaging technique used for real-time tissue assessments in clinical settings. It detects changes in tissue structure and biochemistry without labels, aiding disease monitoring. We are bringing FLIm to the…

Antimicrobial blue light inactivation of microbial pathogens: State of the artAlthough microbiologists have been ringing the alarm bell for years, the threat of antibiotic resistance has reached new prominence in the popular press that the issue should be added to the list of global emergencies. It is now indisputable that…

Traumatic Brain Injury and Alzheimer’s Disease: Vascular Perturbations - Emerging evidence suggests that traumatic brain injury (TBI) and Alzheimer’s Disease (AD) may share similar pathophysiology including long-term alterations in neurodegeneration and cognition. Vascular perturbations are evident in both neurological…

Decoding microbiome-dependent metabolite signaling and immune modulation in the kidney - The kidney plays a central role in clearing chemically diverse small molecules from the body, making it a key site of exposure to both endogenous and microbiome-derived metabolites. These exposures can shape disease progression, particularly…