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Undergraduate Bioengineering Courses

BIEN 001 Introductory Colloquium in Bioengineering

Colloquia on current topics in bioengineering and other related fields delivered at an introductory level. Presented by faculty members, visiting scientists, or individuals with industrial bioengineering experience.

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BIEN 010 Overview of Bioengineering

Provides an overview of the various aspects of bioengineering. Illustrates the application of engineering principles for the design of the various aspects of bioengineering. Illustrates the various products and processes related to the health science industries. Covers diagnostic instruments, artificial organs, biotechnology, and cell and tissue engineering. Covers engineering ethics.

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BIEN 101 Quantitative Biochemistry

Provides Bioengineering students with an in depth experience in applying mathematical modeling and simulation methods to understand the dynamics of biochemical systems. The quantitative approach in this course will prepare bioengineering students for designing new applications of genetic engineering.

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BIEN 105 Circulation Physiology

Introduces tensor and vector mathematics that describe the conservation of momentum and mass transport in biological sciences, the cardiovascular system, and pulmonary system. Includes constitutive equations such as the Navier-Stokes and Casson models, significance of fluid stress in biological vessels, and the physiological relevance of fundamental parameters. Emphasizes the relation between function and system behavior.

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BIEN 110 Biomechanics of the Human Body

Introduces the motion, structure and function of the musculoskeletal system, the cardiovascular system, and the pulmonary system. Topics include applied statics, kinematics, and dynamics of these systems and the mechanics of various tissues (ligament, bone, heart, blood vessels, lung). Emphasis is on the relation between function and material properties of these tissues.

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BIEN 115 Quantitative Physiology

Analyzes engineering aspects of physiological systems and artificial organs. Covers the nervous system, muscular system, cardiovascular system, respiratory system, and renal system. Addresses ethical and professional considerations in the development and utilization of medical devices and interventions.

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BIEN 120 Biosystems and Signal Analysis

Provides basic knowledge for the quantitative analysis of the dynamic behavior of biological systems. Particular applications include neural systems, control of metabolic and hormonal systems, and design of instruments for monitoring and controlling biological systems. Topics include system theory, signal properties, control theory, and transfer functions.

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BIEN 125 Biotechnology & Molecular Bioengineering

Provides an overview of biochemical processes in cells and their use in developing new products and processes. Presents cellular processes such as metabolism, protein synthesis, enzyme behavior, and cell signaling and control from an engineering viewpoint of modeling and control.

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BIEN 130 Bioinstrumentation

Introduces basic components of instruments for biological applications. Explores sources of signals and physical principles governing the design and operation of instrumentation systems used in medicine and physiological research. Topics include data acquisition and characterization; signal-to-noise concepts and safety analysis; and interaction of instrument and environment.

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BIEN 130L Bioinstrumentation Laboratory

Laboratory experience with instrumental methods of measuring biological systems. Introduces various sensors and transducers to measure physical, chemical, and biological properties. Covers reliability, dynamic behavior, and data analysis.

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BIEN 135 Biophysics and Biothermodynamics

An introduction to the application of thermodynamic principles to understanding the behavior of biological systems. Discusses biophysical properties of biomacromolecules, such as proteins, polynucleotides, carbohydrates, and lipids, and methods of characterizing their properties and interactions.

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BIEN 136 Tissue Engineering

Covers progress in cellular and molecular biology, and engineering, to provide the basis for advancing tissue repair and regeneration with the goal of restoring compromised tissue functions. Presents methods for cell culture, tissue design and development, manipulation of the cell/tissue microenvironment, and current strategies for functional reconstruction of injured tissues.

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BIEN 137 Advanced Biomechanics

Mechanical characterization of biological tissues at the cellular, organ, and system levels; exploration of biomechanical factors in physiological and pathological conditions.

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BIEN 138 Fundamental Principles of Wound Repair

Provides fundamental understanding of the molecular and cellular biology of wound repair and regeneration. Focuses on the spatiotemporal roles of inflammatory cytokines; growth factors; extracellular matrix; mechanical forces; tissue cells and adult stem/progenitor cells in soft tissue repair. Topics include embryonic wound regeneration and adult skin and cardiovascular repair.

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BIEN 140A Biomaterials

Covers the principles of materials science and engineering, with attention to topics in bioengineering. Explores atomic structures, hard treatment, fundamentals of corrosion, manufacturing processes, and characterization of materials.

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BIEN 140B Biomaterials

Covers the structure-property relations of metals, ceramics, polymers, and composites, as well as hard and soft tissues such as bone, teeth, cartilage, ligament, skin, muscle, and vasculature. Focuses on behavior of materials in the physiological environment.

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BIEN 142 Introductory Biomedical Optical Imaging

Examines fundamental theory and basic design of biomedical optical imaging systems. Topics include a basic understanding of the working principles of optical components, diagnostic light-tissue interaction, and design of imaging systems to exploit the interaction of light with biological phenomena.

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BIEN 155 Biotechnology Laboratory

Laboratory experience in cell culture, bioreactors, optical techniques, array techniques, and separation and purification methods.

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BIEN 159 Dynamics of Biological Systems

Covers engineering principles for the analysis and modeling of biological phenomena. Topics include molecular diffusion and transport, membranes, ligand-bioreceptor interactions, enzyme kinetics, and dynamics of metabolic pathways. Examines the application of these principles to the design of bioreactors, bioassays, drug delivery systems, and artificial organs.

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BIEN 160 Biomedical Imaging

An introduction to the fundamental physics and engineering principles for medical imaging systems. Covers Xray, ultrasound, radionuclide, magnetic resonance imaging, positron emission tomography, optical coherent tomography, and other optical methods. Includes image formation and reconstruction, image characteristics, and quality and image processing.

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BIEN 165 Biomolecular Engineering

Emphasizes engineering, biochemical, and biophysical concepts and technologies intrinsic to specific topics of biomolecular engineering. Introduces the history of genetic and protein engineering. Topics include biological thermodynamics, molecular kinetics, biochemical and biophysical approaches, protein engineering, high-throughput screening technologies, and protein engineering with unnatural amino acids.

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BIEN 166 Bioinspired Engineering for Sustainable Energy

Introduces the use of concepts from basic biological sciences (including biochemistry and biophysics) for applied energy engineering. Covers biological energy conversion (including photosynthesis) and its implication for sustainable energy technologies. Discusses recent advances in biomimetic and bioinspired energy conversion.

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BIEN 167 Medical Diagnostics

Provides an overview of medical diagnostics. Topics include methods of biochemical detection, genotyping, DNA sequencing, medical imaging, hematology, microfluidics, epidemiology, diagnostics for point-of-care and resource-limited settings, and case studies of commercially successful diagnostic products.

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BIEN 175A/B/C Senior Design

Covers the entire design process for bioengineering. Explores intellectual property, quality control, and regulatory and ethical considerations. Requires working in small teams effectively to prepare formal engineering reports, web pages notebooks, oral presentations, a project demonstration, and a business plan.

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BIEN 190 Special Studies

Provides individual study to meet special curricular needs.

BIEN 197 Research for Undergraduates

Directed research on a topic relevant to bioengineering.

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