University of California, Riverside

Department of Bioengineering

BIG Program Courses

BIG students have the flexibility to study a wide range of courses that can be targeted to the individual student's professional goals. However, so that all BIG students have a fundamental foundation in bioengineering, they must take key courses that will satisfy this core requirement. The elective list is substantially and includes medical school courses offered in the UCR School of Medicine Ph.D. Program in Biomedical Sciences.

Course Enrollment

Core Courses

All BIG students are required to take at least three courses from the following Bioengineering courses. Other courses may be substituted but must be approved by the Bioengineering Graduate Advisor. Students from non-engineering backgrounds are also required to take BIEN 264 or BIEN 270 in addition to the courses stipulated here. M.S. and Ph.D. students alike are expected to complete the course requirements for the programs within their first year of residence.

Other Requirements

Other required courses: One bioscience class chosen from:

  • BCH 210 - Biochemistry of Macromolecules
  • BCH 211 - Molecular Biology
  • BCH 212 - Signal Transduction and Biochemical Regulation
  • BIOL/CMDB 200 - Cell Biology
  • BIOL/CMDB 201 - Molecular Biology
  • BIOL 203 - Cellular Biophysics
  • BIOL 221 - Microbial Genetics
  • NRCS 200A - Fundamentals of Neuroscience
  • Equivalent Selections from Biomedical Sciences Medical School Courses

In addition, BIEN 286-Colloquium in Bioengineering, is required every quarter in which it is offered.

Additional Courses

Additional courses may be required by the Advisory Committee based upon the student's background and fields of interest.

BIG Student Handbook 2018 - 2019

To download the 2018 - 2019 BIG Student Handbook click here 

2018 - 2019 Course Descriptions

BIEN 201 Mathematical Methods for Bioengineering

Provides a fundamental grounding in applied mathematics. Enables the provision of problems in biotransport and bioreaction kinetics. Topics include linear differential equations solutions; analytical methods for partial differential equations including separations of variables, similarity transforms, and perturbation methods; and numerical methods for bioengineering, regression techniques, and error analysis.

BIEN 220 Chemical Genomics Design Studio

Explores chemical genomics research approaches. Emphasizes critical thinking; advanced planning of time-consuming tests of hypotheses and experimental caveats, trade-offs, and options. Taught in a case-study approach, teams consist of students with engineering, biology, computational sciences, and chemical backgrounds. Teams generate an interdisciplinary chemical genomics research project.

BIEN 223 Engineering Analysis of Physiological Systems

Provides a bioengineering approach to the physiological properties and interactions of various mammalian organ systems. Covers the nervous, muscular, cardiovascular, respiratory, and renal systems. Emphasizes the physical and engineering principles governing these systems by applying quantitative and analytical approaches.

BIEN 224 Cellular and Molecular Engineering

Emphasizes biophysical and engineering concepts intrinsic to specific topics at the cellular and molecular level. Includes receptor-ligand dynamics in cell signaling and function; DNA replication and RNA processing; cellular and protein sorting; control of gene expression; membrane structure, transport and traffic; biological signal transduction; and mechanics of cell division.

BIEN 227 Biophotonics: Laser-Tissue Interactions and Therapeutic Applications

Provides an overview of various types of interactions between lasers and biological tissues. Addresses methods of optical property measurements, mathematical modeling of light propagation, and selected therapeutic applications of lasers. Includes one or two field trips to medical laser centers to observe laser treatment procedures.

BIEN 228 Biophotonics: Optical Diagnosis and Measurements

Covers the fundamentals underlying optical diagnostic procedures, including absorption and scattering-based techniques. Also addresses physics of optical tweezers and their applications in biological sciences.

BIEN 233 Computational Modeling of Biomolecules

Introduces computational methods for the quantitative analysis of biomolecular structures at atomic resolution. Aids in understanding the physicochemical properties of biomolecular function, the prediction of biological properties, and the design of new experiments. Forms the basis for structure-based design of proteins with tailored properties and inhibitors of protein function.

BIEN 234 Orthopaedic Regenerative Engineering and Mechanobiology

Introduces advanced biomechanics and mechanobiology of skeletal tissues including bone and cartilage. Provides an understanding of structure-function relationship in biological tissues. Focuses on bone and cartilage regenerative engineering approaches based on scaffolds, stem cells, and mechanotransduction.

BIEN 235 Vascular Biomechanics and Engineering

Provides detailed understanding of the crucial role of mechanical forces in guiding blood vessel formation and function in human health and disease. Topics include embryogenesis, wound repair, atherosclerosis, and cancer. Addresses the principles of biomaterials science and regenerative medicine for promoting therapeutic neovascularization.

BIEN 236 Nanomaterials for Regenerative Medicine

Covers recent advances in nanomaterial synthesis, fabrication, and characterization. Focuses on the medical applications of nanomaterials and nanotechnologies. Addresses methods of synthesis of nanomaterials such as nanoparticles, nanotubes, and nanofibers. Includes critical design criteria and assessment methods for properties of nanomaterials to meet medical requirements.

BIEN 237 Medical Diagnostics

Provides an in-depth analysis of current topics in medical diagnostics. Focuses on critical reviews of recent journal articles on diagnostics and case studies of recent commercial diagnostic products. Topics include methods of biochemical detection, genotyping, DNA sequencing, medical imaging, hematology, microfluidics, epidemiology, and diagnostics for point-of-care and resource-limited settings.

BIEN 242 Advanced Biomedical Optical Imaging

Examines advanced theory and optimized design of biomedical optical imaging systems. Topics include a full understanding of the working principles of optical components, diagnostic light-tissue interaction, and design of imaging systems to exploit the interaction of light with biological phenomena.

BIEN 245 Optical Methods in Biology, Chemistry, and Engineering

Covers the origin of fluorescence and other emission processes that modulate the characteristics of molecular emissions. Presents emission-based analytical and bioanalytical methods and techniques. Reviews state-of-the-art instrumentation, including their applicability, limitations, and source. Also provides interpretation and meaning of the measured signals as applied to biological systems.

BIEN 249 Integration of Computational and Experimental Biology

A multidisciplinary introduction to computational methods used to analyze experimental biological data. Introduction to mathematical concepts needed to understand protein structure and dynamics, protein-protein interactions (structures and networks), gene regulatory networks, signal transduction networks, metabolic networks, and kinetic modeling of cellular processes. Also covers techniques used to derive experimental data.

BIEN 251 Biophotonics: Optical Microscopy and its Biological Applications

Examines the fundamentals of optical system design and system integration in light microscopy. Covers design components, including light sources, lenses, mirrors, dispersion elements, optical fibers, and detectors. Also covers optical system analysis, transfer functions, magnification, resolution, contrast, and molecular, cellular, organ, and organism applications.

BIEN 260 Special Topics in Bioinstrumentation

Focuses on advanced technologies in bioengineering studies, such as spectroscopy, microscopy, magnetic resonance imaging, computed tomography, ultrasonography, and biosensors.

BIEN 261 Special Topics in Biotransport

Focuses on advanced methods of analysis of biological transport phenomena such as drug distribution, microcirculation, membrane transport, and transport in organs and tissues.

BIEN 262 Special Topics in Biosignaling

Focuses on current research in cell signaling and control, including G protein-coupled receptors, signal transduction and cytoskeletal dynamics, and cell adhesion and cell metabolism.

BIEN 263 Special Topics in Biocomputation

Focuses on various advanced methods for computational studies of biomolecules and simulations; molecular dynamics simulations; Brownian dynamics simulations; Monte Carlo methods; normal mode analysis; electrostatic calculations; and free energy calculations.

BIEN 264 Biotransport Phenomena

Covers the mathematical expression and modeling of principles underlying the transport processes of biological systems and biomedical engineering processes. Emphasizes momentum, mass transport, and interpretation of these processes. Topics include advanced development of governing conservation equations and the appropriate constitutive equations for transport in circulation and tissue.

BIEN 265 Special Topics in Biomedical Optical Imaging

Focuses on advanced theory, technolo¬gy, and applications of biomedical optical imaging. Addresses novel sources of optical contrast, current developments in optical imaging instrumentation, and recent advances in their application to bioengineering.

BIEN 266 Special Topics in Biological Nuclear Magnetic Resonance (NMR) Spectroscopy

Focuses on various advanced methods for the determination of structure, dynamics, and interactions of biomolecules. Utilizes multidimensional and multinuclear NMR spectroscopy.

BIEN 267 Special Topics in Biophotonics

Focuses on advanced science and technology methods that use electromagnetic radiation for medical and biological applications. Covers photonic devices, detection, microscopy and spectroscopy techniques, and diagnostics and mechanistic ideas on photodynamic therapy.

BIEN 268 Bioengineering Experimentation and Analysis

Introduces measurement principles and data acquisition methods related to biomechanics and biochemical and bioelectrical signals from living systems. Addresses the fundamental mechanisms underlying the operation of various sensor types and the modern instruments illustrating noise analysis, filtering, signal processing, and conditioning. Includes experiments aimed at investigating physical responses of cells and tissues to a variety of stimuli.

BIEN 269 Special Topics in Optical Measurements and Photomedicine

Focuses on the applications of optical trapping methods to characterize the mechanical and electromechanical properties of biological cells and membranes, as well as to quantify molecular interactions. Also covers the use of optical probes for cellular and tissue imaging, as well as optical therapy.

BIEN 270 Transport with Reactions in Biological Systems

Covers the mathematical expression and modeling of principles underlying the transport processes of biological systems reactions and biomedical engineering processes involving reactions. Topics include advanced development of chemical kinetics and reaction mechanisms of biological systems; enzymatic reactions; Michaelis-Menton kinetics; and cell-surface ligand-receptor kinetics.

BIEN 271 Video Bioinformatics: Multi-scale Analysis of Biological Systems

Introduces the significant range for both the time and spatial scales of biological systems. Includes video imaging techniques, as well as how these spatial and time scales are analyzed for a better understanding of biological function.

BIEN 272 Special Topics in Biomaterials and Tissue Engineering

Focuses on advanced biomaterials and tissue engineering for medical applications. Explores the design, processing, characterization, and evalu¬ation of biomaterials. Examines current development in novel materials and recent advances in their applications in tissue engineering, drug delivery, gene therapy, cell therapy, medical devices, and implants.

BIEN 273 Special Topics in Regenerative Engineering and Biomechanics

Focuses on advanced regenerative engineering and biomechanics in the skeletal system. Examines biomechanics of skeletal system at the tissue and cell levels utilizing molecular biology approaches. Develops and implements regenerative methodologies for repairing damaged skeletal tissues by a thorough understanding in mechanobiology.

BIEN 274 Special Topics in Endothelial Biomedicine

Presents an integrated view of the fundamental role of endothelial cells in regulating vascular tone, inflammation, and repair in both health and disease. Encompasses the principles related to developmental biology, molecular and cellular biology, biomechanics, bioengineering, and translational med¬icine.

BIEN 286 Colloquium in Bioengineering

Colloquia on current research topics in bioengineering and other related fields. Presented by faculty members and visiting scientists.

BIEN 290 Directed Studies

Faculty-directed individual study of selected topics in Bioengineering

BIEN 297 Directed Research

Prerequisite(s): graduate standing; consent of instructorResearch conducted under the supervision of a faculty member on selected problems in bioengineering.

BIEN 298-I Individual Internship

An individual apprenticeship in bioengineering with an approved professional individual or organization and academ¬ic work under the direction of a faculty member. Requires a written report. Graded Satisfactory (S).

BIEN 299 Research for Thesis or Dissertation

Designated for research in bioengineering for the M.S. thesis or Ph.D. dissertation

BIEN 302 Teaching Practicum

Provides supervised teaching in undergraduate courses.

BIEN 401 Fundamentals of Proposal Preparation and Ethical Standards in Bioengineering

An introduction to effective proposal preparation and writing for bioengineering-related research. Also covers ethical standards of scientific research related to bioengineering.

BIEN 402 Effective Writing for Bioengineering Research Publications

An introduction to effective manuscript writing for bioengineering-related research publications.

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Department Information

Department of Bioengineering
205 Materials Science & Engineering

Hours: 8:00 AM - 5:00 PM
Tel: (951) 827-4303
Fax: (951) 827-6416

Potential Undergraduate Students:
Undergraduate Admissions

Potential Graduate Students:
Professor Victor G. J. Rodgers

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