Title: Magnetic Resonance Fingerprinting of Coronary Artery Disease

Abstract: Coronary artery disease remains the leading cause of death in the world. Early detection and characterization
of the coronary artery disease is important for proper treatment. Coronary artery disease is caused by the development
of atherosclerosis or plaque on the wall of the coronary arteries, which causes partial obstruction to blood flow in the
coronary arteries, myocardial ischemia/infarction, and various degrees of myocardial tissue damage and functional
impairment. Magnetic resonance imaging (MRI) has been used to image coronary arteries and characterize myocardial
tissue properties. MRI can noninvasively detect biomarkers of high risk coronary artery plaques that may cause major
cardiac events in the future. It can also accurately detect myocardial blood flow reduction and the resulting myocardial
structural remodeling such as fiber orientation changes and tissue damages such as fibrosis and necrosis. It also allows
evaluation of impaired ventricular function. An overview of various MRI techniques to image the coronary artery and
myocardial tissue will be provided. Technical challenges and future developments will be discussed.

Biography: Debiao Li, PhD received his PhD in Biomedical Engineering at the University of Virginia in 1992. He was an
Assistant Professor of Radiology at Washington University in St. Louis (1993-1998), Associate Professor (1998-2004),
Professor (2004-2010) of Radiology and Biomedical Engineering, and Director of Cardiovascular MR Research (2004-
2010) at Northwestern University, Chicago. Since 2010, Dr. Li has been the Inaugural Director of the Biomedical Imaging
Research Institute and Storz Endowed Chair in honor of George Berci at Cedars- Sinai Medical Center, Los Angeles,
Professor of Medicine and Bioengineering at the University of California, Los Angeles. Dr. Li has published more than 270
research articles and 19 book chapters. He has received more than $30M of research funding from National Institutes of
Health. Dr. Li served as President of the International Society for Magnetic Resonance in Medicine (ISMRM) (2011-
2012), the premier professional society that promotes innovation, development, and application of magnetic resonance
techniques in medicine and biology throughout the world. He also served as President of the Society for Magnetic
Resonance Angiography (2006-2007), President of the Overseas Chinese Society for MR in Medicine (OCSMRM) (2006-
2008), and member of Board of Trustees, Society for Cardiovascular Magnetic Resonance (SCMR) (2009-2012).
He is Associate Editor of Magnetic Resonance in Medicine (MRM) and the Journal of Magnetic Resonance Imaging
(JMRI). He is a fellow of ISMRM and American Institute for Medical and Biological Engineering. He is widely recognized as
a leader in cardiovascular MR research, including coronary artery imaging, atherosclerosis imaging, myocardial blood
flow measurement, and non-contrast MR angiography.