RNA regulation at the single molecule level: from nuclear organization to molecular activity: Cellular behavior depends on the activities of countless individual biomolecules. Compared to population-based methods, the ability to simultaneously perturb and analyze individual molecules provides a more direct and quantitative…

TITLEEngineering Synthetic RNA Controllers for Biosensing Gene Regulation and Targeted TherapiesABSTRACT     Synthetic RNA circuits are engineered to precisely control cellular information flow, with applications in biosensing, gene therapy, and biomanufacturing. To design and implement RNA-based input/output…