Cells as Bio-Factories to Heal Wounds
Abstract: Chronic wounds are skin injuries that recur or fail to heal by 6 weeks. These wounds affect 6.5 million patients in the US and this number is growing rapidly due to a drastic increase in the number of diabetics, the obese, and the elderly, all populations in which wound…
Diversification and Compartmentalization: Two Synthetic Biology Technologies for Redesigning Cells
Abstract: I will discuss two technologies my lab is developing to gain control over cellular behaviors, particularly engineered metabolism. The first is an in vivoCRISPR-guided DNA polymerase we call…