Title: Dancing with a moving target: Disrupting brain tumors   Abstract: Brain tumors present a clinical challenge due to their propensity to be highly invasive and distributed at the time of detection. Our laboratory is exploring a variety of engineering strategies to control, contain and arrest tumor cell invasion in…

Title: Efficient generation and phenotyping of genome- edited rodent models using CRISPR-Cas9 in a high throughput pipeline   Abstract: The emergence of CRISPR-based endonuclease technology represents a paradigm shift in our approach to generating animal models that precisely recapitulate human disease. CRISPR-Cas9 has…